The sky is pretty much the limit with SMs. If you can make it work and its suitable for 13+ then sure go for it.
As far as a suicide case, you would need either someone else to accuse, difficult in a suicide case or have the the victim be able to show up on the suspects list to be able to accuse. Attempted suicide for example could potentially work because you would still be able to question the victim as a suspect or assisted suicide may work because you could accuse the person who helped.
If all else fails you could put the suicide story with another crime (someone commits suicide because he is suspected of the murder and you find out who the real murderer is etc)
Hope that makes sense :)